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If OHSS does not improve with outpatient care, the woman may be treated in the hospital with close monitoring. The doctor may order intravenous IV fluids and medicines for nausea and may remove fluid from the abdomen. Other supportive therapy may be given as needed. Complications from OHSS can be severe. You may become dehydrated and pressure in your abdomen may increase from too much fluid.

These problems can lead to blood clots forming within the blood vessels. Blood clots can travel to your lungs or to other important organs. This can be potentially life-threatening. These complications can usually be avoided by recognizing the signs, symptoms, and laboratory evidence that OHSS is getting worse and getting appropriate treatment.

OHSS symptoms usually appear a few days after ovulation. Symptoms usually resolve within two weeks, unless pregnancy occurs. Pregnant women often continue to have symptoms for weeks or more after a positive pregnancy test. The symptoms gradually go away, and the rest of the pregnancy is not affected.

There are several strategies used to lower the risk of OHSS. However, the uterus and ovaries returned to normal 4 weeks later. Ours is the longest reported case of megalocystic ovaries. There has been no report of or guidance regarding the treatment of persistent megalocystic ovaries lasting such a long time in IVF patients.

The team finally chose the puncture and GnRH agonist protocol based on the high level of hormones in the cystic fluid. Although these hormones were not increased in the blood, the E 2 levels were quite high in the follicles. The cumulative effect of such high hormone levels in so many cysts might have an important role in maintaining enlarged ovaries. Both ovaries shrank somewhat after surgery, and they gradually returned to normal size during follow-up after three doses of GnRH agonists, which validated our method.

In conclusion, hyperstimulated, enlarged ovaries and their complications could be persistent during and even after pregnancy when IVF is involved. The risks of malignancy and torsion must be kept in mind, but should not lead to unnecessary surgery.

Long-term follow-up of IVF patients is recommended. Ovarian hyperstimulation syndrome. J Hum Reprod Sci. Ovarian hyperstimulation syndrome: steps to maximize success and minimize effect for assisted reproductive outcome.

Fertil Steril. Article PubMed Google Scholar. Ovarian hyperstimulation syndrome: pathophysiology and prevention. J Assist Reprod Genet. The pathophysiology of ovarian hyperstimulation syndrome: an unrecognized compartment syndrome. Spontaneous ovarian hyperstimulation syndrome and hyperreaction luteinalis are entities in continuum. Ultrasound Obstet Gynecol. Badawy A, Elnashar A.

Treatment options for polycystic ovary syndrome. Int J Womens Health. Renal and hepatic functions after a week of controlled ovarian Hyperstimulation during in vitro fertilization cycles. Int J Fertil Steril. Adnexal masses in pregnancy: an updated review. Avicenna J Med. Acute abdomen in the 17 th week of twin pregnancy due to ovarian torsion — a late complication of IVF. Geburtshilfe Frauenheilkd. Society of American Gastrointestinal Endoscopic Surgeons. Guidelines for diagnosis, treatment, and use of laparoscopy for surgical problems during pregnancy.

Surg Endosc. Ovarian torsion in infertility management-missing the diagnosis means losing the ovary: a high price to pay. Persistent megalocystic ovary following in vitro fertilization in a postpartum patient with polycystic ovarian syndrome. Taiwan J Obstet Gynecol. Bilateral megalocystic ovaries following in vitro fertilization detected during cesarean section: a case presentation.

J Turk Ger Gynecol Assoc. Persistent ascites resolving with gonadotropin-releasing-hormone-agonist 18 months after hospitalization for severe ovarian hyperstimulation syndrome. Arch Gynecol Obstet. Download references. The authors thank the patient for agreeing to the publication of the case and are grateful to their colleagues who helped in the preparation of the manuscript.

The datasets used during the current study are available from the corresponding author on reasonable request. You can also search for this author in PubMed Google Scholar. RX contributed to the pathology of ovarian tissue. All authors contributed to the drafting and critical revision of the manuscript. All authors read and approved the final manuscript. Correspondence to Rong Chen. Informed consent was obtained from the patient for publication of this case report and any accompanying images.

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Reprints and Permissions. Shi, J. Persistent megalocystic ovaries after ovarian hyperstimulation syndrome in a postpartum patient with polycystic ovarian syndrome: a case report.

J Ovarian Res 11, 79 Download citation. Received : 02 May Accepted : 27 August Published : 10 September The good news is that most women with OHSS have mild symptoms pain, diarrhoea, nausea, headache and hot flushes and can be treated easily. Only about one to two percent of women undergoing ovarian stimulation suffer severe OHSS, some of the symptoms are listed below. No treatment can stop OHSS, but treatment can help ease symptoms and prevent problems.

It will get better with time. Most of your symptoms should ease in a few days. If you have mild OHSS, you can be looked after at home. If you become pregnant, OHSS can get worse and last up to a few weeks or longer.

Stay in touch with your doctor if you have OHSS and tell them if you develop new symptoms. Be aware that you can get better, then worse.

Doctors can help to detect women who are at risk of OHSS before ovarian stimulation starts. You can develop OHSS immediately after your eggs are taken. This is because the empty follicles from where they retrieved the eggs fill with fluid.

This causes the ovaries to swell they are already swollen and the pain starts. Fluid leaks from your ovaries, creating discomfort and bloating. If tests show that you have too many follicles, delaying egg retrieval can lower the risk of OHSS. Blood tests should be taken regularly to check your level of oestrogen. Once it has fallen to an acceptable level, ovarian stimulation can start again.

OHSS tends to happen after the trigger shot. Sometimes, depending on circumstances, a clinic will recommend an alternative to gonatrophin medication known as hCG as a trigger shot. Mild stimulation IVF is an option where a woman is given a lower dose of fertility drugs called a GnRH agonist, such as Lupron over a shorter period of time than with conventional IVF — five to nine days rather than the standard four to six weeks.

Similar to IVF but the eggs are matured in the laboratory, not in the ovaries. This requires less medication for a shorter period of time, reducing the risk of OHSS.

Eggs are fertilised in the lab and allowed to develop for three to five days, then transferred back into the uterus. Success rates are similar to traditional IVF. When ready, you can have a frozen embryo transfer FET. Not all embryos are suitable for freezing. All embryos must make it to blastocyst day 5 to be frozen. Ask your clinic about how they deal with women who have OHSS.

I hope this is helpful. OHSS was horrible, but fortunately it can be treated. It could be a life saver. Save my name, email, and website in this browser for the next time I comment. Wonderful news for former Strictly Come Dancing stars Ola and James Jordan as they announced they are expecting their first child via IVF The couple, who have been together more than 20 years, have been trying for a Natalie Fitzpatrick starts her 6th round of IVF this week.

After 5 previous unsuccessful cycles and recurrent miscarriages, Natalie has been advised to have preimplantation genetic screening.



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